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azythromycin [2018/09/25 01:32] – created Scott Larsonazythromycin [2025/11/03 16:06] (current) Scott Larson
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-====== Oral Azithromycin for Blepharokeratoconjunctivitis in Children ====== +====== Azithromycin for Blepharokeratoconjunctivitis in Children ====== 
-  * Azithromycin 5mg/kg/day+  * Oral Azithromycin 5mg/kg/day
   * Once daily dosing   * Once daily dosing
   * Recheck in monthly intervals   * Recheck in monthly intervals
   * May combine with other topical anti-inflammatory treatment as needed   * May combine with other topical anti-inflammatory treatment as needed
  
 +====Side Effects====
 +  * GI (most common): diarrhea 5%, nausea 4%, abdominal pain 3%, vomiting 1%, dyspepsia, flatulence, constipation, hyptertrophic pyloric stenosis in neonates
 +  * Skin: Rash, puritis, photosensitivity, angioedema. erythema multiforme, Stevens-Johnson, toxic epidermal necrolysis, DRESS
 +  * CNS: headache, dizzines, fatigue, exacerbation of myasthenia gravis 
 +  * Hepatotoxicity
 +  * Heart: QT prolongation and arrhythmias 
 +  * Hearing: hearing loss and tinnitus
 +  * Psychiatric- anxiety, aggression
 ===== Sources ===== ===== Sources =====
-[[https://doi.org/10.1016/j.jaapos.2012.10.015|Oral azithromycin combined with topical anti-inflammatory agents in the treatment of blepharokeratoconjunctivitis in children.JAAPOS 2013 Feb;17(1):112-3]]+[[https://doi.org/10.1016/j.jaapos.2012.10.015|Oral azithromycin combined with topical anti-inflammatory agents in the treatment of blepharokeratoconjunctivitis in children.JAAPOS 2013 Feb;17(1):112-3]]\\ 
 +[[https://www.aaojournal.org/article/S0161-6420(15)01303-2/pdf|Oral Antibiotics for Meibomian Gland-Related Ocular Surface Disease (AAO OTA)]] 
 + 
 +{{tag>drugs, blepharitis}}