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behcets [2020/01/24 21:48] Scott Larsonbehcets [2025/06/03 03:12] (current) – [Ocular Findings] Scott Larson
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-====== Behçet'Disease ======+====== Behçet Disease ======
  
-  * Inflammatory disorder of blood vessels characterized by: +  * Systemic vascular inflammatory disorder affecting skin, mucous membranes, eyes, lungs, GI tract and CNS. It is characterized by: 
     * Mouth sores- aphthous ulcers usually first sign     * Mouth sores- aphthous ulcers usually first sign
     * Genital sores- (75%) small ulcers on scrotum or labia     * Genital sores- (75%) small ulcers on scrotum or labia
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     * Also puss filled bumps in the skin     * Also puss filled bumps in the skin
     * Arthritis     * Arthritis
 +  * Typically symptoms start in the 20's or 30's
 +====Ocular Findings====
     * Ocular Inflammation (66%)     * Ocular Inflammation (66%)
       * Conjunctivitis        * Conjunctivitis 
       * Uveitis       * Uveitis
 +        * Hypopion
         * Panuveitis with vasculitis          * Panuveitis with vasculitis 
-    * Rare associations +    * Complications of uveitis 
-      inflammation of the brain or spinal cord +          * cataracts, synechiae, band keratopathy 
-      * blood clots, aneurism, GI vasculitis +====Other More Rare Findings==== 
-    Typically symptoms start in the 20's or 30's+  Inflammation of the brain or spinal cord 
 +  * blood clots, aneurism, GI vasculitis 
 + 
 +====Etiology==== 
 +  Unknown autoimmune disorder 
 +  * Associated with the HLA-B51/B5 allele 
 +    * 57% of people with this genotype have Behçet syndrome 
 + 
 +====Resources==== 
 +[[https://www-clinicalkey-com.slhs.idm.oclc.org/#!/content/clinical_overview/67-s2.0-0dc07703-d4fd-4a55-a3b1-e8d2954751c7|Clinical Key Monograph]] 
 + 
 +{{tag>syndrome uveitis}}