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foveal_hypoplasia [2023/09/26 16:25] Scott Larsonfoveal_hypoplasia [2026/02/02 19:35] (current) – [Systemic Associations] Scott Larson
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   * [[incontientia_pigmenti|Incontientia pigmenti]]   * [[incontientia_pigmenti|Incontientia pigmenti]]
   * Prematurity   * Prematurity
-  * Stickler Syndrome+  * [[stickler_syndrome|Stickler Syndrome]]
  
 ==== Diagnostic Procedures ==== ==== Diagnostic Procedures ====
Line 35: Line 35:
   * Ophthalmoscopy   * Ophthalmoscopy
     * absence of foveal reflex and foveal avascular zone and typical macular pigment     * absence of foveal reflex and foveal avascular zone and typical macular pigment
-  * OCT+  * [[optical_coherence_tomography|OCT]]
     * Absence of foveal pit, persistent inner retinal layers through fovea      * Absence of foveal pit, persistent inner retinal layers through fovea 
 +    * Example of an OCT report of a child with foveal hypoplasia
 +{{::foveal_hypoplasia.jpg}}
 +
   * OCT-A   * OCT-A
     * absence of superficial capillary plexus and variable decrease in deep capillary plexus in the fovea     * absence of superficial capillary plexus and variable decrease in deep capillary plexus in the fovea
  
 ==== References ==== ==== References ====
-  * [[https://www.sciencedirect.com/science/article/pii/S0161642019322122?via%3Dihub|Study of the Leicester Grading system, Rufai et al 2020]] +  * [[https://pubmed.ncbi.nlm.nih.gov/31937464/|Rufai SR, Thomas MG, Purohit R, Bunce C, Lee H, Proudlock FA, Gottlob I. Can Structural Grading of Foveal Hypoplasia Predict Future Vision in Infantile Nystagmus?: A Longitudinal Study. Ophthalmology. 2020 Apr;127(4):492-500.]] 
-    * Rufai SR, Thomas MG, Purohit R, Bunce C, Lee H, Proudlock FA, Gottlob I. Can Structural Grading of Foveal Hypoplasia Predict Future Vision in Infantile Nystagmus?: A Longitudinal Study. Ophthalmology. 2020 Apr;127(4):492-500. doi10.1016/j.ophtha.2019.10.037. Epub 2019 Nov 4. PMID: 31937464PMCIDPMC7105819+  * [[https://1drv.ms/b/c/31d83ae8e55e0542/EX01u0C3NulLoi7a60eswF8B-5H80Fsu4n4Cjz_gID-mMg?e=rHWQFw |Hendrickson A, Possin D, Vajzovic L, Toth CAHistological development of the human fovea from midgestation to maturityAm J Ophthalmol 2012;154:767-778.e2.]]