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relative_potency_opioids [2025/09/03 20:39] – Scott Larsonrelative_potency_opioids [2025/09/03 22:38] (current) – Scott Larson
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 ====== Relative Potency of Opioids ====== ====== Relative Potency of Opioids ======
-fixme + 
-ANALGESIC POTENCY RELATIVE TO MORPHINE DURATION OF ACTION (HOURS)b +^ANALGESIC^POTENCY RELATIVE TO MORPHINE^DURATION OF ACTION (HOURS)^ 
-Codeine +|Codeine Dihydrocodeine|1/10|3-6| 
-Dihydrocodeine 1/10 3-6 +|Pethidine|1/8|2-4| 
-Pethidine 1/8 2-4 +|Tapentadol|1/3|4-6| 
-Tapentadol 1/3 4-6 +|Hydrocodone|2/3|4-8| 
-Hydrocodone +|Oxycodone|1.5|3-4| 
-(not United Kingdom) 2/3 4-8 +|Methadone|5-10d|8-12| 
-Oxycodone 1.5(2)c 3-4 +|Hydromorphone|4-5|4-5| 
-Methadone 5-10d 8-12 +|Buprenorphine (SL)|80|6-8| 
-Hydromorphone 4-5 (5-7.5)d 4-5 +|Buprenorphine(TD)|100|Formulation dependent (72-168)| 
-Buprenorphine (SL) 80 6-8 +|Fentanyl (TD)|100|72| 
-Buprenorphine (TD) 100 (75-115)c Formulation dependent (72-168) + 
-Fentanyl (TD) 100 (150)c 72+[[https://www.ncbi.nlm.nih.gov/books/NBK537482/table/appannex6.tab2/|From WHO Guidelines for the Pharmacological and Radiotherapeutic Management of Cancer Pain in Adults and Adolescents. Table A6.2]]