====== Behçet Disease ======

  * Systemic vascular inflammatory disorder affecting skin, mucous membranes, eyes, lungs, GI tract and CNS. It is characterized by: 
    * Mouth sores- aphthous ulcers usually first sign
    * Genital sores- (75%) small ulcers on scrotum or labia
    * Erythema Nodosum- painful red skin nodules 
    * Also puss filled bumps in the skin
    * Arthritis
  * Typically symptoms start in the 20's or 30's
====Ocular Findings====
    * Ocular Inflammation (66%)
      * Conjunctivitis 
      * Uveitis
        * Hypopion
        * Panuveitis with vasculitis 
    * Complications of uveitis
          * cataracts, synechiae, band keratopathy
====Other More Rare Findings====
  * Inflammation of the brain or spinal cord
  * blood clots, aneurism, GI vasculitis

====Etiology====
  * Unknown autoimmune disorder
  * Associated with the HLA-B51/B5 allele
    * 57% of people with this genotype have Behçet syndrome

====Resources====
[[https://www-clinicalkey-com.slhs.idm.oclc.org/#!/content/clinical_overview/67-s2.0-0dc07703-d4fd-4a55-a3b1-e8d2954751c7|Clinical Key Monograph]]

{{tag>syndrome uveitis}}