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Intermediate Uveitis Causes

  • Intraocular lymphoma. (CBC with differential)
  • Lyme disease (antibody test)
  • toxocariasis (antibody test)
  • syphilis (antibody test)
  • bartonellosis (antibody test)
  • Multiple sclerosis (MRI brain, HLA-DR2 and HLA-DR15)
  • Sarcoidosis (ACE may be elevated normally, Chest Xray)
  • Necrotizing systemic vasculitis
  • Behçets disease
  • Eales disease
  • Collagen vascular diseases (HLA-B27)
    • Ankylosing Spondylitis
    • Inflammatory Bowel Diseases - (Ulcerative colitis, Crohn disease)
    • Psoriatic arthritis

Masqueraders

  • Endophthalmitis- suspect in the setting of recent surgery or intraocular injection, immunocompromised or parenteral nutrition or central line

Idiopathic

  • Pars planitis

Pediatric

  • typically idiopathic
  • most common association: JIA

Reference: AAO Wiki Page: Pediatric Intermediate Uveitis