Iris Heterochromia (ddx)

  • Benign idiopathic heterchromia (most common)
    • genetic mosaicism or developmental variation
  • Ocular melanocytosis
  • Iris Nevus
  • Iris Melanoma
  • Iris Atrophy
    • Trauma
    • Fuchs' heterochomic iridocyclitis
      • Chronic unilateral anterior uveitis, iris atrophy and stellate keratic precipitates
  • Siderosis- intraocular hemorrhage or iron deposition from intraocular foreign body
  • Medications
    • Chronic prostaglandin analogues in one eye in a partially pigmented iris
  • Horner syndrome- lack of pigmentation of iris in congenital Horner syndrome
  • Waardenburg syndome
  • Syndromic Hirschsprung Disease