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  1. Trace
  2. Ocular Complications from Chemotherapeutic Agents

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Table of Contents
  • MEK inhibitors
  • References

Ocular Complications from Chemotherapeutic Agents

MEK inhibitors

  • Selumetinib, Binimetinib, Trametinib, Cobimetinib
    • Blurred vision, diplopia, eyelid edema, subconjunctival hemorrhage, increased lacrimation
    • Retinal pigment epithelial detachment, Central serous-like retinopathy

References

  • Ocular toxicities of MEK inhibitors and other targeted therapies. Stjepanovic et al. Annals of Oncology.Volume 27, Issue 6, June 2016, Pages 998-1005
  • Clinical and Morphological Characteristics of MEK Inhibitor-Associated Retinopathy. Francis, Jasmine H. et al. Ophthalmology. 2017-12, Vol.124 (12), p.1788-1798
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